منابع مشابه
Pharmacokinetics and analgesic effect of slow-release oral morphine sulphate in volunteers.
Sustained-release oral morphine sulphate (MST) 20 mg was administered to 11 healthy volunteers. Mean peak plasma morphine concentration was 14.8 ng ml-1, and occurred at a mean time of 142.5 min after ingestion. Analgesia assessed by an ischaemic forearm pain test increased to a maximum approximately 40 min after the calculated peak plasma concentration of morphine had been achieved, and remain...
متن کاملComparison of Efficacy Between Oral Morphine Sulphate
Aim: to prospectively evaluate degree of pain during transrectal ultrasound-guided prostate biopsy after receiving analgesics treatment of oral morphine sulphate compared to suppository sodium diclofenac. Methods: the study group comprised 60 consecutive men subjects (median age 67.8 years) undergoing transrectal prostate biopsy. They were randomized into two groups; group 1 received oral analg...
متن کاملPostoperative absorption of controlled-release morphine sulphate. A study in patients given no parenteral opioids.
The absorption of morphine sulphate in a controlled-release formulation was studied in 12 patients who had undergone unilateral inguinal hernia repair under a light general anaesthetic and ilio-inguinal block. Serum morphine concentrations were measured serially and gastric emptying was assessed by measurement of paracetamol absorption. Three patients had delayed gastric emptying and impaired m...
متن کاملAbsorption of controlled release morphine sulphate in the immediate postoperative period.
The absorption of morphine sulphate, given orally as a controlled release preparation, was studied in 10 patients who had undergone peripheral vascular surgery with a standard opioid-based general anaesthetic technique. Serum morphine concentrations were measured (high pressure liquid chromatography) every 2 h for the first 16 h after surgery and the results were strongly suggestive of a decrea...
متن کاملEffect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets
BACKGROUND Injections of mixtures prepared from crushed tablets contain insoluble particles which can cause embolisms and other complications. Although many particles can be removed by filtration, many injecting drug users do not filter due to availability, cost or performance of filters, and also due to concerns that some of the dose will be lost. METHODS Injection solutions were prepared fr...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1985
ISSN: 0007-0912
DOI: 10.1093/bja/57.9.858